Retinal ischemia as the first manifestation of antiphospholipid antibody syndrome

P46: Optic Neuritis as the First Manifestation of the Primary Antiphospholipid Antibody Syndrome

Optic neuritis is commonly associated with diseases such as Multiple Sclerosis, infections, taking special drugs, etc. but recently we have observed a patient that presented retro bulbar optic neuritis as a manifestation of antiphospholipid syndrome. A 35 y/o young woman with the history of chickenpox admitted to the Qhaem hospital (Mashhad, Iran) with the c/o progressive pain and blurred visio...

Acute adrenal failure secondary to bilateral infarction of the adrenal glands as the first manifestation of primary antiphospholipid antibody syndrome.

Adrenal insuYciency is an uncommon, life threatening complication of the primary antiphospholipid antibody syndrome (PAPS), secondary to either adrenal haemorrhage or infarction. Adrenal failure more often follows other PAPS thromboembolic manifestations, and has to be clearly diVerentiated from other PAPS abdominal emergencies, including mesenteric and hepatic infarction. 3–5 The pathological ...

ANTIPHOSPHOLIPID ANTIBODY SYNDROME-A CASE OF AORTIC VALVE INSUFFICIENCY

A 31 year old woman was hospitalized for evaluation of aortic valve insufficiency and her present cardiac status. Clinical and paraclinical findings strongly suggested the presence of a collagen vascular inflammatory processprecisely, the antiphospholipid antibody syndrome (APS), with systemic lupus erythematosus as the underlying disease.

Widespread cutaneous necrosis as the first clinical manifestation of secondary antiphospholipid syndrome.

Antiphospholipid syndrome (APS) is an acquired prothrombotic state characterized by recurrent thromboses, pregnancy loss, thrombocytopenia, and the presence of antiphospholipid antibodies, anticardiolipin antibodies, lupus anticoagulant and/or anti2-glycoprotein antibody. The original clinical and laboratory criteria for APS, called the Sapporo criteria, were first published in 1999. These were...

Acute renal failure as first clinical manifestation of the primary antiphospholipid syndrome.